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Homepage Point of care QuikRead QuikRead CRP

QuikRead CRP

QuikRead CRP test is intended for quantitative measurement of C-reactive protein (CRP) in whole blood, plasma and serum samples with the QuikRead 101 instrument. This simple and robust system gives reproducible results in just a few minutes.

QuikRead CRP kit box
  • Generally
  • Technical data
  • Controls and related products
  • About C-reactive protein (CRP)
  • Antimicrobial resistance and CRP
  • Documents and materials
  • Frequently asked questions

Generally

Measurement of CRP can be helpful in the clinical management of a patient with infection symptoms. CRP is normally present in low concentrations in the blood of healthy people. CRP concentrations are markedly increased in the event of bacterial infection, whereas viral infections normally induce only a modest elevation or no elevation at all.

QuikRead CRP is a simple test for quantitative measurement of CRP. The system - consisting of a small instrument and a ready-to-use kit - is designed for use in primary healthcare settings. When the test is performed near the patient, the result is available during patient consultation and can, therefore, guide antibiotic use.

QuikRead CRP provides you with

Reliability

  • As accurate as a laboratory test
  • Reproducible CRP result within 8 - 160 mg/l range

Speed

  • Result available when needed - in less than 3 minutes

Ease of use

  • The system is easy to operate, even by non-laboratory personnel
  • Performed on a finger prick blood sample (alternatively serum or plasma sample)
  • Built-in calibration

Test results should never be used alone, without a complete clinical evaluation.

QuikRead CRP is not registered in the USA.

Technical data

Products available
  • 134191 QuikRead CRP (prefilled) with capillaries and plungers, 50 tests
  • 134192 QuikRead CRP (prefilled), without capillaries and plungers, 50 tests
  • 67961 QuikRead CRP (buffer bottle), with capillaries and plungers, 50 tests
UseFor in vitro diagnostic use
MethodImmunoturbidimetric
Sample typeWhole blood, serum, plasma
Instrument informationQuikRead 101 Instrument
Time to resultLess than 3 minutes
Reading of the resultInstrument read
Storage2 - 8 °C
Shelf life15 months (theoretical)
Transportation2 - 8 °C
Size and weight190 x 140 x 80 mm
Additionally needed
  • QuikRead Instrument (with dispenser, 1 ml) 06040
  • QuikRead Instrument (without dispenser, 1 ml) 06078
  • QuikRead dispenser, 1 ml 05560
  • Capillaries 67962, supplied with product 67961
  • Plungers 67966, supplied with product 67961
  • QuikRead CRP Control 154812
Full export carton of kits576/672
Country of originFinland
RegistrationNot registered in the USA
Registered trademarkQuikRead is a registered trademark of Aidian Oy

Controls and related products

Regular use of QuikRead CRP Control is recommended.

Recommended Controls:

  • 154812 QuikRead CRP Control (~40 mg/l with blue colour)

About C-reactive protein (CRP)

CRP aids clinical management of patients with infections or inflammatory conditions

C-reactive protein (CRP) is an acute-phase plasma protein present in healthy individuals at low concentrations. The median CRP level of healthy people is usually < 0.8 mg/l1 but the concentration increases fast during bacterial infection, being able to go up to hundreds of mg/l. Bacterial infections and inflammatory conditions stimulate the production of CRP in the liver. From the initial stimulus, CRP levels become detectable in 4-6 hours and peak in 36-48 hours2,3. CRP production is proportional to the intensity of infection and inflammation. Therefore, it is useful in the evaluation of disease severity. In bacterial infections, CRP may increase relatively high, above 100 mg/l. Viral and self-limiting bacterial infections cause only a minor elevation or not elevation at all. In inflammatory conditions, CRP levels may increase to moderate level, usually being between 10-40 mg/l. When the patient starts responding to treatment, the immune system overcomes the pathogen itself, or the inflammatory stimulus starts settling, CRP levels decrease rapidly back to normal with a half-life of 19h1,2.

Accurate and precise CRP point of care testing is helpful in the clinical management of patients with infection and in optimizing antibiotic prescribing. The short analytical time and a small sample volume of CRP point of care tests offer a substantial benefit compared to the laboratory CRP test. When used together with the clinical examination of a patient, QuikRead go CRP tests are excellent tools in the following situations:

  • differentiation of bacterial and viral infections
  • decreasing diagnostic uncertainty and guiding appropriate antibiotic prescribing in acute infections4,5
  • evaluation, monitoring, and prediction of the infection course, inflammation and treatment response6-8
  • ruling out severe bacterial infection9

References

  1. Shine, B et al. Solid phase radioimmunoassays for C-reactive protein. Clin. Chim. Acta 1981; 117:13–23.
  2. Vigushin DM, Pepys MB, Hawkins PN. Metabolic and scintigraphic studies of radioiodinated human C-reactive protein in health and disease. J Clin Invest 1993; 91(4): 1351-1357.
  3. Pepys MB, Hirschfield GM. C-reactive protein: a critical update. J Clin Invest 2003; 111(12): 1805-1812.
  4. Markanday A. Acute Phase Reactants in Infections: Evidence-Based Review and a Guide for Clinicians. Open Forum Infect Dis 2015; 2(3): ofv098.
  5. Little P et al. Effects of internet-based training on antibiotic prescribing rates for acute respiratory-tract infections: a multinational, cluster, randomised, factorial, controlled trial. Lancet 2013; 382(9899): 1175-1182.
  6. Tonkin-Crane SKG et al. Clinician-targeted interventions to influence antibiotic prescribing behaviour for acute respiratory infections in primary care: an overview of systematic reviews (Review). Cohcrane Database of Systematic Reviews 2017; 7(9): CD012252.
  7. Bruns AH et al. Usefulness of consecutive C-reactive protein measurements in follow-up of severe community-acquired pneumonia. Eur Respir J 2008; 32(3): 726-732.
  8. Verhagen DW et al. Prognostic value of serial C-reactive protein measurements in left-sided native valve endocarditis. Arch Intern Med 2008; 168(3): 302-307.
  9. Emery P. Evidence-based review of biologic markers as indicators of disease progression and remission in rheumatoid arthritis. Rheumatol Int 2007; 27(9): 793-806.

Antimicrobial resistance and CRP

Antimicrobial resistance is a global health threat. CRP point of care testing aids management of respiratory infections and fighting against antimicrobial resistance.
Learn more: Antimicrobial resistance and CRP

Documents and materials

Marketing and sales materials

QuikRead go Control Information (EN)

Instructions for Fingertip Blood Collection (EN)

Instructions for use

(For informative use only. Kindly always refer to the latest package insert in the kit.)

QuikRead CRP Prefilled Cuvettes IFU (FI, SE, NO, DK), 134191, 134192

QuikRead CRP Prefilled Cuvettes IFU (GB, DE, FR, IT), 134191, 134192

QuikRead CRP Prefilled Cuvettes IFU (CZ, SK, HU, PL), 134191, 134192

QuikRead CRP Prefilled Cuvettes IFU (SI, RS, HR, GR), 134191, 134192

QuikRead CRP Prefilled Cuvettes IFU (ES, PT, NL, GB), 134191, 134192

QuikRead CRP Control IFU (GB, DE, FR, ES, IT, CZ, SK, SI, SR, EE, SE, NO, DK, FI), 154812

Revision history QuikRead CRP Control 154812: new instructions for use

Safety Data Sheet

QuikRead CRP Prefilled Cuvettes SDS (EN) 134191, 134192

QuikRead CRP SDS (EN) 67961

QuikRead CRP Control SDS (EN) 154812

Frequently asked questions

The QuikRead instrument gives me a result of > 160 mg/l, but I would like to get an exact CRP result. Is it possible?

When using plasma/serum samples you can dilute the sample with 0.9% NaCl before adding it to the cuvette. The recommended dilution is 1+1. Remember to multiply the result by 2.

I accidentally left a QuikRead CRP kit at room temperature for a weekend. Can I still use it?

Yes, you can use the kit. The kit can be stored at room temperature (18 - 25 °C) for one month. When used at room temperature during daily working hours (7.5 hours) and stored at +2 - +8 °C after finishing, the kit will remain stable for 3 months.

I have used a 20 µl sample volume for plasma patient samples. Is the result I get the final result?

No, when using a 20 µl plasma volume, the result should be multiplied by 0.6. When using a 12 µl plasma or serum volume, the result can be directly read from the screen and no additional calculations are needed.

Interested in these products? Please contact

  • Head office
  • Contact in your country

Aidian Oy

Koivu-Mankkaan tie 6 B,
FI-02200 Espoo,
Finland

P.O. Box 83,
FI-02101 Espoo,
Finland

+358 10 309 3000

Invoicing addresses

E-invoice
Basware 003718552161

Invoicing address
Aidian Oy,
P.O. Box 33,
FI-02101 Espoo,
Finland

Business ID FI18552161

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