QuikRead go wrCRP+Hb
QuikRead go wrCRP+Hb is a fast and easy to use test for quantitative determination of C-reactive protein (CRP) values in whole blood, serum, and plasma and haemoglobin in whole blood with the QuikRead go instrument. The test gives reliably two results, the wide range CRP and the Hb, from one sample with one analysis.
Accurate measurement of C-reactive protein (CRP) can be critical in the management of a patient with symptoms of an infection. The QuikRead go wrCRP+Hb test helps to identify patients who benefit from antibiotics and it is valuable in monitoring the treatment outcome. The easy-to-use QuikRead go wrCRP+Hb test can be used near the patient and it provides immediate wrCRP and Hb result.
QuikRead go wrCRP+Hb has wide measuring range which covers for both high sensitive and conventional CRP tests. Modest increase in CRP levels within the high sensitivity range of 1-5 mg/l may indicate low level inflammation and aid in cardiovascular risk assessment1.
Hemoglobin measurement gives important information about the patient’s condition in both acute and basic healthcare settings. Changes in hemoglobin concentrations can be seen in several medical conditions which make hemoglobin measurement one of the most commonly used diagnostic test.
QuikRead go wrCRP+Hb is an efficient tool for point of care settings to guide the treatment decisions of healthcare professionals.
QuikRead go wrCRP+Hb provides reliable and fast results
One fast analysis – two results
- A single analysis provides both CRP and hemoglobin results
- Combined analysis time 2 minutes
- Performed on a finger-prick blood sample. Venous blood, plasma, or serum can also be used
- Wide CRP measuring range 0.5 - 200 mg/l and hemoglobin 50 - 220 g/l
- Provides more information for making treatment decisions
Wide measuring range
- Combines high sensitive and conventional CRP tests
- Enables detection of low level inflammation
Easy sample collection
- A small sample volume (10 µl) approximates to a drop of blood
- A single sample collection minimises patient discomfort
Storage at room temperature up to +25°C
- Enables immediate use
QuikRead go multianalyte point of care system
- Easy to use
- Portable instrument and fully automatic testing procedure
- Bi-directional connectivity to most HIS and LIS systems
Test results should never be used alone, without a complete clinical evaluation.
QuikRead go wrCRP+Hb is not registered in the USA.
- Emerging Risk Factors Collaboration. C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis. Lancet 2010; 375:132-140.
|Use||For in vitro diagnostic use|
|Sample type||Whole blood, plasma and serum (CRP) Whole blood (Hb)|
QuikRead go Instrument
|Time to result||2 minutes|
|Reading of the result||Instrument read|
|Storage||2 - 25 ºC|
|Shelf life||15 months|
|Transportation||2 - 25 ºC|
|Size and weight||190 x 140 x 80 mm / 0.497 kg|
|Full export carton of kits||576/672|
|Country of origin||Finland|
|Registration||Not registered in the USA|
|Registered trademark||QuikRead go is a registered trademark of Aidian Oy|
About C-reactive protein (CRP)
CRP aids clinical management of patients with infections or inflammatory conditions
C-reactive protein (CRP) is an acute-phase plasma protein present in healthy individuals at low concentrations. The median CRP level of healthy people is usually < 0.8 mg/l1 but the concentration increases fast during bacterial infection, being able to go up to hundreds of mg/l. Bacterial infections and inflammatory conditions stimulate the production of CRP in the liver. From the initial stimulus, CRP levels become detectable in 4-6 hours and peak in 36-48 hours2,3. CRP production is proportional to the intensity of infection and inflammation. Therefore, it is useful in the evaluation of disease severity. In bacterial infections, CRP may increase relatively high, above 100 mg/l. Viral and self-limiting bacterial infections cause only a minor elevation or not elevation at all. In inflammatory conditions, CRP levels may increase to moderate level, usually being between 10-40 mg/l. When the patient starts responding to treatment, the immune system overcomes the pathogen itself, or the inflammatory stimulus starts settling, CRP levels decrease rapidly back to normal with a half-life of 19h1,2.
Accurate and precise CRP point of care testing is helpful in the clinical management of patients with infection and in optimizing antibiotic prescribing. The short analytical time and a small sample volume of CRP point of care tests offer a substantial benefit compared to the laboratory CRP test. When used together with the clinical examination of a patient, QuikRead go CRP tests are excellent tools in the following situations:
- differentiation of bacterial and viral infections
- decreasing diagnostic uncertainty and guiding appropriate antibiotic prescribing in acute infections4,5
- evaluation, monitoring, and prediction of the infection course, inflammation and treatment response6-8
- ruling out severe bacterial infection9
- Shine, B et al. Solid phase radioimmunoassays for C-reactive protein. Clin. Chim. Acta 1981; 117:13–23.
- Vigushin DM, Pepys MB, Hawkins PN. Metabolic and scintigraphic studies of radioiodinated human C-reactive protein in health and disease. J Clin Invest 1993; 91(4): 1351-1357.
- Pepys MB, Hirschfield GM. C-reactive protein: a critical update. J Clin Invest 2003; 111(12): 1805-1812.
- Markanday A. Acute Phase Reactants in Infections: Evidence-Based Review and a Guide for Clinicians. Open Forum Infect Dis 2015; 2(3): ofv098.
- Little P et al. Effects of internet-based training on antibiotic prescribing rates for acute respiratory-tract infections: a multinational, cluster, randomised, factorial, controlled trial. Lancet 2013; 382(9899): 1175-1182.
- Tonkin-Crane SKG et al. Clinician-targeted interventions to influence antibiotic prescribing behaviour for acute respiratory infections in primary care: an overview of systematic reviews (Review). Cohcrane Database of Systematic Reviews 2017; 7(9): CD012252.
- Bruns AH et al. Usefulness of consecutive C-reactive protein measurements in follow-up of severe community-acquired pneumonia. Eur Respir J 2008; 32(3): 726-732.
- Verhagen DW et al. Prognostic value of serial C-reactive protein measurements in left-sided native valve endocarditis. Arch Intern Med 2008; 168(3): 302-307.
- Emery P. Evidence-based review of biologic markers as indicators of disease progression and remission in rheumatoid arthritis. Rheumatol Int 2007; 27(9): 793-806.
Hemoglobin is the molecule that contains iron and transports oxygen in the blood. It binds oxygen in the lungs, transports it to tissues and returns carbon dioxide from tissues to the lungs. Hemoglobin has an important role in the body’s iron cycle and it contains most of the functional iron in the body.
If a patient has anemia the blood hemoglobin or red blood cell concentration is below recommended levels. Anemia has many different causes but iron deficiency, which causes iron deficiency anemia, is the most common cause in the Western world. It should be remembered that anemia is more of a symptom than a disease. Hemoglobin tests may help diagnose anemia but the cause of anemia has to be investigated.
- Dacie and Lewis. Practical Haematology, 11th edition, 2012.
- HoffBrand and Pettit. Essential Haematology, 3rd edition, 1997.
- Ruutu. Rajamäki, Lassila, Porkka. Veritaudit, 3rd edition, 2007.
Antimicrobial resistance and CRP
Antimicrobial resistance is a global health threat. CRP point of care testing aids management of respiratory infections and fighting against antimicrobial resistance.
Learn more: Antimicrobial resistance and CRP
Documents and materials
Marketing and sales materials
Instructions for use
(For informative use only. Kindly always refer to the latest package insert in the kit.)
Safety Data Sheet
Frequently asked questions
I would like to start using the QuikRead go wrCRP+Hb tests. Which instrument software version I need on my QuikRead go instrument?
You should have the version 7.5.1.
I have updated my QuikRead go instrument into version 7.5.1 to start using the QuikRead go wrCRP+Hb test. However, now I noticed I have still some QuikRead go CRP+Hb kits in fridge. Can I use these kits still after the software update?
Yes, in addition to the QuikRead go wrCRP+Hb tests, you can use the QuikRead go CRP and QuikRead go CRP+Hb kits with the QuikRead go instrument software version 7.5.1.
I accidentally left a QuikRead go wrCRP+Hb kit at room temperature for a weekend. Can I still use it?
Yes, you can use the kit. The unopened kit can be stored at cool or room temperature (2-25 ºC) until the expiry date marked on the kit label. After the first opening of the kit components, the cuvettes can be kept at room temperature (18-25) for 3 months. The reagent caps for 6 months. See more information in the package insert.
What happens if I accidentally use the 20 µl capillaries with the QuikRead go wrCRP+Hb test?
It is important to use only the 10 µl capillaries with orange stripe, which are inside the QuikRead go wrCRP+Hb test kit. The 20 µl capillaries have a blue stripe and are to be used with QuikRead go CRP test only. The instrument measures the haematocrit value and above the upper limit (75%), it will not give results. If you dispense twice the amount of sample, the instrument thinks the haematocrit value is double what it actually is. The HCT correction is able to correct only those sample results, which have hematocrit below 37.5%.