QuikRead go CRP+Hb
QuikRead go CRP+Hb is a fast and easy-to-use test for quantitative determination of C-reactive protein (CRP) values in whole blood, serum, and plasma and haemoglobin (Hb) in whole blood with the QuikRead go instrument. The test gives reliably two results, CRP and Hb, from one sample with one analysis.
Accurate measurement of C-reactive protein (CRP) can be critical in the management of a patient with symptoms of an infection. The QuikRead go CRP+Hb test helps to identify patients who benefit from antibiotics and it is valuable in monitoring the treatment outcome. The easy to use QuikRead go CRP+Hb test can be used near the patient and it provides immediate CRP and hemoglobin result.
Hemoglobin measurement gives important information about the patient’s condition in both acute and basic healthcare settings. Changes in hemoglobin concentrations can be seen in several medical conditions which make hemoglobin measurement one of the most commonly used diagnostic test.
QuikRead go CRP+Hb is an efficient tool for point of care settings to guide the treatment decisions of healthcare professionals.
QuikRead go CRP+Hb provides reliable and fast results
One fast analysis – two results
- A single analysis provides both CRP and hemoglobin results
- Combined analysis time 2 minutes
- Performed on a finger-prick blood sample. Venous blood, plasma, or serum can also be used
- CRP measuring range 5 - 200 mg/l and hemoglobin 50 - 245 g/l
- Provides more information for making treatment decisions
- Single sample collection minimises patient discomfort
Easy to use
- No manual steps
- Automatic hematocrit correction for CRP results
QuikRead go multianalyte point of care system
- Portable instrument and fully automatic testing procedure
- Bi-directional connectivity to most HIS and LIS systems
Test results should never be used alone, without a complete clinical evaluation.
QuikRead go CRP+Hb is not registered in the USA.
|Use||For in vitro diagnostic use|
Immunoturbidimetric and photometric
|Sample type||CRP: whole blood, serum, plasma. Hb: whole blood.|
QuikRead go Instrument
|Time to result||2 minutes|
|Reading of the result||Instrument read|
|Storage||2 - 8 °C|
|Shelf life||15 months (theoretical)|
|Transportation||2 - 8 °C|
|Size and weight||190 x 140 x 80 mm / 0.515 kg|
|Full export carton of kits||576/672|
|Country of origin||Finland|
|Registration||Not registered in the USA|
|Registered trademark||QuikRead go is a registered trademark of Aidian Oy|
About C-reactive protein (CRP)
CRP aids clinical management of patients with infections or inflammatory conditions
C-reactive protein (CRP) is an acute-phase plasma protein present in healthy individuals at low concentrations. The median CRP level of healthy people is usually < 0.8 mg/l1 but the concentration increases fast during bacterial infection, being able to go up to hundreds of mg/l. Bacterial infections and inflammatory conditions stimulate the production of CRP in the liver. From the initial stimulus, CRP levels become detectable in 4-6 hours and peak in 36-48 hours2,3. CRP production is proportional to the intensity of infection and inflammation. Therefore, it is useful in the evaluation of disease severity. In bacterial infections, CRP may increase relatively high, above 100 mg/l. Viral and self-limiting bacterial infections cause only a minor elevation or not elevation at all. In inflammatory conditions, CRP levels may increase to moderate level, usually being between 10-40 mg/l. When the patient starts responding to treatment, the immune system overcomes the pathogen itself, or the inflammatory stimulus starts settling, CRP levels decrease rapidly back to normal with a half-life of 19h1,2.
Accurate and precise CRP point of care testing is helpful in the clinical management of patients with infection and in optimizing antibiotic prescribing. The short analytical time and a small sample volume of CRP point of care tests offer a substantial benefit compared to the laboratory CRP test. When used together with the clinical examination of a patient, QuikRead go CRP tests are excellent tools in the following situations:
- differentiation of bacterial and viral infections
- decreasing diagnostic uncertainty and guiding appropriate antibiotic prescribing in acute infections4,5
- evaluation, monitoring, and prediction of the infection course, inflammation and treatment response6-8
- ruling out severe bacterial infection9
- Shine, B et al. Solid phase radioimmunoassays for C-reactive protein. Clin. Chim. Acta 1981; 117:13–23.
- Vigushin DM, Pepys MB, Hawkins PN. Metabolic and scintigraphic studies of radioiodinated human C-reactive protein in health and disease. J Clin Invest 1993; 91(4): 1351-1357.
- Pepys MB, Hirschfield GM. C-reactive protein: a critical update. J Clin Invest 2003; 111(12): 1805-1812.
- Markanday A. Acute Phase Reactants in Infections: Evidence-Based Review and a Guide for Clinicians. Open Forum Infect Dis 2015; 2(3): ofv098.
- Little P et al. Effects of internet-based training on antibiotic prescribing rates for acute respiratory-tract infections: a multinational, cluster, randomised, factorial, controlled trial. Lancet 2013; 382(9899): 1175-1182.
- Tonkin-Crane SKG et al. Clinician-targeted interventions to influence antibiotic prescribing behaviour for acute respiratory infections in primary care: an overview of systematic reviews (Review). Cohcrane Database of Systematic Reviews 2017; 7(9): CD012252.
- Bruns AH et al. Usefulness of consecutive C-reactive protein measurements in follow-up of severe community-acquired pneumonia. Eur Respir J 2008; 32(3): 726-732.
- Verhagen DW et al. Prognostic value of serial C-reactive protein measurements in left-sided native valve endocarditis. Arch Intern Med 2008; 168(3): 302-307.
- Emery P. Evidence-based review of biologic markers as indicators of disease progression and remission in rheumatoid arthritis. Rheumatol Int 2007; 27(9): 793-806.
Antimicrobial resistance and CRP
Antimicrobial resistance is a global health threat. CRP point of care testing aids management of respiratory infections and fighting against antimicrobial resistance.
Learn more: Antimicrobial resistance and CRP
Hemoglobin is the molecule which contains iron and transports oxygen in the blood. It binds oxygen in the lungs, transports it to tissues and returns carbon dioxide from tissues to the lungs. Hemoglobin has an important role in the body’s iron cycle and it contains most of the functional iron in the body.
If a patient has anemia the blood hemoglobin or red blood cell concentration is below recommended levels. Anemia has many different causes but iron deficiency, which causes iron deficiency anemia, is the most common cause in the Western world. It should be remembered that anemia is more of a symptom than a disease. Hemoglobin tests may help diagnose anemia but the cause of anemia has to be investigated.
- Dacie and Lewis. Practical Haematology, 11th edition, 2012.
- HoffBrand and Pettit. Essential Haematology, 3rd edition, 1997.
- Ruutu. Rajamäki, Lassila, Porkka. Veritaudit, 3rd edition, 2007.
Documents and materials
Marketing and sales materials
Instructions for use
(For informative use only. Kindly always refer to the latest package insert in the kit.)
Safety Data Sheet
Frequently asked questions
I opened the lid of a cuvette but I did not use the cuvette immediately. How long is the cuvette usable?
You should use the cuvette within 2 hours of opening it.
Can I use CRP controls with the QuikRead go CRP+Hb test kit?
Yes, you can use the same CRP controls with the QuikRead go CRP and QuikRead go CRP+Hb tests. The target values are valid for both tests.
Do I get a hemoglobin result automatically from every measurement if I use QuikRead go CRP+Hb test?
Yes, you automatically get both CRP and hemoglobin results each time from whole blood samples. If plasma or serum samples are used, you only receive a CRP result. This is because plasma and serum samples do not contain red blood cells and, therefore, do not contain hemoglobin.
Is it enough to take only one capillary sample (not two replicates) to get a reliable hemoglobin result?
We have evaluated the difference between parallel samples with the QuikRead go CRP+Hb test and we do not see any need for two or more parallel samples. The Hb results received with the QuikRead go CRP+Hb test are comparable to laboratory results and to the gold standard methods, and they require a single sample only. It is always important to pay attention to proper sampling technique.