QuikRead go easy CRP
The QuikRead go easy CRP is an easy to use and reliable point-of-care test, which gives quantitative CRP test results within 2 minutes. The unique one-step Sample Collector used with the QuikRead go easy CRP minimizes hands-on steps and enables fast and easy CRP testing.
Quantitative measurement of CRP concentration has been reported to be a sensitive indicator of the efficacy of antimicrobial therapy and the course of bacterial infections, as well as an effective tool in controlling and monitoring postoperative infections1-5. Modestly elevated CRP values have been shown to be clinically relevant e.g. in neonatal sepsis6-8, and conditions that include systemic inflammation (such as COPD9-11 and Rheumatoid arthritis11,13).
QuikRead go easy CRP provides you with
Unique one-step Sample Collector
- Fast and easy sample collection improves workflow
- Convenient for the patient
Room temperature storage up to +25 °C
- Easy to store in the health care unit
- Enables immediate use, no need to warm up the reagents
Reliable CRP results in minutes
- CRP measuring range from whole blood is 1−200 mg/l and 1−120 mg/l with serum or plasma samples
QuikRead go multianalyte point-of-care system
- Portable and fully automatic point-of-care system
- Bi-directional connectivity to most HIS and LIS systems
Test results should never be used alone, without a complete clinical evaluation.
QuikRead go easy CRP is not registered in the USA.
- van Leeuwen MA & van Rijswijk MH. Acute phase proteins in the monitoring of inflammatory disorders. Baillieres Clin Rheumatol. 1994; 8 (3): 531–52.
- Olaison L et al. Fever C-reactive protein and other acute-phase reactants during treatment of infective endocarditis. Arch Intern Med. 1997; 157 (8): 885–92.
- Peltola H et al. Simplified treatment of acute staphylococcal osteomyelitis of childhood. Pediatrics.1997; 99 (6): 846–50.
- Philip AGS & Mills PC. Use of C-reactive protein in minimizing antibiotic exposure: Experience with infants initially admitted to a well-baby nursery. Pediatrics. 2000; 106 (1): 1–5.
- Pepys MB. The acute phase response and C-reactive protein. In: Warrell DA, Cox TM, Firth JD, Benz EJ, (eds). Oxford Textbook of Medicine, 4th ed. Oxford University Press, 2003; 2: 150–6.
- Chiesa C et al. C reactive protein and procalcitonin: Reference intervals for preterm and term newborns during the early neonatal period. Clin Chim Acta. 2011; 412 (11-12): 1053–9.
- Hofer N et al. Non-infectious conditions and gestational age influence C-reactive protein values in newborns during the first 3 days of life. Clin Chem Lab Med. 2011; 49 (2): 297–302.
- Wasunna A et al. C-reactive protein and bacterial infection in preterm infants. Eur J Pediatr.1990; 149 (6): 424−7.
- Pinto-Plata VM et al. C-reactive protein in patients with COPD, control smokers and nonsmokers. Thorax. 2006; 61 (1): 23–8.
- Mannino DM et al. Obstructive and restrictive lung disease and markers of inflammation: data from the Third National Health and Nutrition Examination. Am J Med. 2003; 114 (9): 758–62.
- Dahl M et al. C-reactive protein as a predictor of prognosis in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2007; 175 (3): 250−5.
- Dessein PH et al. High sensitivity C-reactive protein as a disease activity marker in rheumatoid arthritis. J Rheumatol. 2004; 31 (6): 1095−7.
- Poole CD et al. The association between C-reactive protein and the likelihood of progression to joint replacement in people with rheumatoid arthritis: a retrospective observational study. BMC Musculoskelet Disord. 2008; 9: 146.
|Use||For in vitro diagnostic use|
|Sample type||Whole blood, serum, plasma|
QuikRead go Instrument
|Time to result||2 minutes|
|Reading of the result||Instrument read|
|Storage||2 - 25 ºC|
|Shelf life||15 months|
|Transportation||2 - 25 ºC|
|Size and weight||190 x 140 x 80 mm / 0.550 kg|
|Full export carton of kits||576/672|
|Country of origin||Finland|
|Registration||Not registered in the USA|
|Registered trademark||QuikRead go is a registered trademark of Aidian Oy|
Specific features of CRP (C-reactive protein)
- normally present in very low concentrations in the blood of healthy people; 99% have levels of <10 mg/l 1 and 90 % have levels < 3 mg/l2.
- uncomplicated viral infections mostly induce (with some exceptions) a very modest elevation or none at all1
- in bacterial infections, concentrations increase markedly1
- elevated concentrations can be detected within 6 - 12 h after onset of an inflammatory stimulus, reaching maximum within 24 - 48 h3, 4
- rise in concentrations corresponds to severity of infection1
- concentrations fall rapidly when the patient responds to antibiotic treatment1
- normalisation of the concentration may indicate that the duration of the treatment has been sufficient and the treatment can be discontinued1,5,6
- in a big part of septic neonates the concentrations are below 6 mg/l 7,8,9
- Pepys MB. The acute phase response and C-reactive protein. In: Warrell DA, Cox TM, Firth JD, Benz EJ, eds. Oxford Textbook of Medicine, 4th ed. Oxford University Press, 2003. Vol 2, p.150 - 156.
- Shine, B., de Beer, FC., Pepys, MB. Solid phase radioimmunoassays for C-reactive protein. Clin Chim Acta, 1981,117: 13 - 23.
- Bjerrum L. C-reactive protein measurement in general practice may lead to lower antibiotic prescribing for sinusitis. Br J Gen Pract 2004; 54: 659 - 662.
- Pepys MB. C-reactive protein fifty years on. Lancet 1981; 1: 653 - 657.
- Philip AGS, Mills PC. Use of C-reactive Protein in Minimizing Antibiotic Exposure: Experience With Infants Initially Admitted to a Well-Baby Nursery. Pediarics 2000; 106.
- Ehl S et al. C-Reactive Protein Is a Useful Marker for Guiding Duration of Antibiotic Therapy in Suspected Neonatal Bacterial Infection. Pediatrics 1997; 99: 216 - 221.
- Hofer, N., Müller, W., Resch, B.Non-infectious conditions and gestational age influence C-reactive protein values in newborns during the first 3 days of life. Clin Chem Lab Med, 2011,49: 297 - 302.
- Wasunna, A., Whitelaw, A., Gallimore, R., Hawkins, PN., Pepys, MB. C-reactive protein and bacterial infection in preterm infants. Eur J Pediatr, 1990, 149: 424 - 427.
- Mathers, NJ., Pohlandt, F. Diagnostic audit of C-reactive protein in neonatal infection. Eur J Pediatr, 1987, 146: 147 - 151.
Antibiotics and CRP
Antibiotics are a cornerstone of the management of bacterial infections. 80 - 90% of antibiotics are prescribed in primary care, and up to 80% of these are used to treat acute respiratory tract infections1. It is estimated that approximately 50% of all antibiotic prescriptions are unnecessary2. Although most of both upper and lower respiratory tract infections are self-limiting and caused by viruses, antibiotics are frequently used to treat these conditions. Unnecessary and inappropriate use of antibiotics favours the emergence and spread of resistant bacteria. Antibiotic resistance is a major public health concern, which could cause harm to a large number of patients worldwide if infections are no longer susceptible to common medicines used to treat them. Therefore, antibiotics should be used with caution and only when necessary3.
The use of antibiotics in primary care varies considerably between countries, which is unlikely to be caused by differences in the frequency of bacterial infections. There is a clear correlation between the use of antibiotics and the emergence of antibiotic resistance4-6. As stated by the World Health Organization (WHO)3, restricting an inappropriate and excessive antibiotic use is important to slow down or even reverse the development of antibiotic resistance.
The QuikRead go CRP test helps healthcare professionals to identify those patients who need - and particularly those who do not need - antibiotic therapy. It is also important to know whether the antibiotics will affect the course of the illness7,8. QuikRead go CRP is useful for following up the effect of treatment. With accurate information, patients can be more easily reassured that symptomatic treatment will be sufficient. On the other hand, a high QuikRead go CRP reading would suggest a bacterial infection requiring antibiotic treatment.
- Goossens HF, M.; Vander, S.R.; Elseviers, M. Outpatient antibiotics use in Europe and association with resistance: a cross-national database study. Lancet 2005; 365:579-587.
- Centers for Disease Control and Prevention (CDC). Antibiotic Resistance Threats in the United States 2013.
- World Health Organization. Antimicrobial resistance: global report on surveillance 2014.
- Goossens H. Antibiotic consumption and link to resistance. Clin Microbiol Infect 2009; 15 Suppl 3:12-15.
- European Centre for Disease Prevention and Control. Antimicrobial consumption. Annual epidemiological report for 2016. Stockholm, 2018.
- Bronzwaer SLAM, Cars O, Buchholz U et al. A European study on the relationship between antimicrobial use and antimicrobial resistance. Emerging infectious diseases 2002; 8:278-282.
- Bruns AH, Oosterheert JJ, Hak E, Hoepelman AI. Usefulness of consecutive C-reactive protein measurements in follow-up of severe community-acquired pneumonia. Eur Respir J 2008; 32:726-732.
- Coelho L, Povoa P, Almeida E et al. Usefulness of C-reactive protein in monitoring the severe community-acquired pneumonia clinical course. Crit Care 2007; 11:R92.
Documents and materials
Marketing and sales materials
QuikRead go easy CRP Test Procedure Video (EN)
Video on YouTube: QuikRead go easy CRP Test Procedure
Instructions for use
(For informative use only. Kindly always refer to the latest package insert in the kit.)
Safety Data Sheet
Frequently asked questions
I would like to start using the QuikRead go easy CRP test. Which instrument software version I need on my QuikRead go instrument?
You should have the version 7.6.2. or newer. This software is suitable also for all of the other test kits that we provide.
Can I store QuikRead go easy CRP kits at room temperature?
Yes, the unopened kits can be stored at cool or room temperature (2…25 ºC) until the expiry date marked on the kit label. After the first opening of the kit components, the cuvettes can be kept at room temperature (18…25 ºC) for 3 months. The reagent caps for 6 months. Sample Collectors can be stored at 2…25 ºC until the expiry date of the kit. See more information in the package insert.
Why does the sample collector not disturb the measurement?
The Sample Collector stays in the cuvette during the whole measurement. The accuracy of the measurement is not affected because the Sample Collector does not hit the light path of the instrument.
Which sampling device is suitable for the QuikRead go easy CRP test?
QuikRead go Sample Collectors 10µl, which are included in the QuikRead go easy CRP test kit, must be used for sampling and adding the sample or control into the QuikRead go easy CRP cuvettes. Other sampling devices or capillaries are not suitable for this test.