QuikRead go easy CRP

Accurate measurement of C-reactive protein (CRP) can be critical in the management of a patient with symptoms of an infection. The QuikRead go easy CRP test helps to identify patients who benefit from antibiotics and it is valuable in monitoring the treatment outcome. The easy to use QuikRead go easy CRP test can be used near the patient and it provides immediate CRP result.

QuikRead go easy CRP is an efficient tool for point of care settings to guide the treatment decisions of healthcare professionals.

QuikRead go easy CRP provides reliable and fast results

Fast and easy sample collection

• Unique one-step sample collector eases the sample collection and improves workflow
• Small sample volume (10 μl) approximates to a drop of blood
• Performed on a finger-prick blood sample. Venous blood, plasma, or serum can also be used

Reliable results within minutes

• Analysis time 2 minutes
• CRP measuring range 1−200 mg/l

Storage at room temperature up to +25 °C

• Enables immediate use

QuikRead go multianalyte point of care system

• Easy to use
• Portable instrument and fully automatic testing procedure
• Bi-directional connectivity to most HIS and LIS systems

Test results should never be used alone, without a complete clinical evaluation.

QuikRead go easy CRP is not registered in the USA.

Regular use of QuikRead go CRP Controls is recommended.

The Controls available are:

• 153764 QuikRead go CRP Control (~25 mg/l with blue colour) (image)
  
• 153763 QuikRead go CRP Control High (~75 mg/l with blue colour) (image)
  
• 153765 QuikRead go CRP Control Low (~2.5 mg/l with blue colour) (image)
  

Related products

• 153211 QuikRead go Sample Collector 10µl (image)
  

CRP aids clinical management of patients with infections or inflammatory conditions

C-reactive protein (CRP) is an acute-phase plasma protein present in healthy individuals at low concentrations. The median CRP level of healthy people is usually < 0.8 mg/l¹ but the concentration increases fast during bacterial infection, being able to go up to hundreds of mg/l. Bacterial infections and inflammatory conditions stimulate the production of CRP in the liver. From the initial stimulus, CRP levels become detectable in 4-6 hours and peak in 36-48 hours^2,3. CRP production is proportional to the intensity of infection and inflammation. Therefore, it is useful in the evaluation of disease severity. In bacterial infections, CRP may increase relatively high, above 100 mg/l. Viral and self-limiting bacterial infections cause only a minor elevation or not elevation at all. In inflammatory conditions, CRP levels may increase to moderate level, usually being between 10-40 mg/l. When the patient starts responding to treatment, the immune system overcomes the pathogen itself, or the inflammatory stimulus starts settling, CRP levels decrease rapidly back to normal with a half-life of 19h^1,2.

Accurate and precise CRP point of care testing is helpful in the clinical management of patients with infection and in optimizing antibiotic prescribing. The short analytical time and a small sample volume of CRP point of care tests offer a substantial benefit compared to the laboratory CRP test. When used together with the clinical examination of a patient, QuikRead go CRP tests are excellent tools in the following situations:

• differentiation of bacterial and viral infections
• decreasing diagnostic uncertainty and guiding appropriate antibiotic prescribing in acute infections^4,5
• evaluation, monitoring, and prediction of the infection course, inflammation and treatment response^6-8
• ruling out severe bacterial infection⁹

References

1. Shine, B et al. Solid phase radioimmunoassays for C-reactive protein. Clin. Chim. Acta 1981; 117:13–23.
2. Vigushin DM, Pepys MB, Hawkins PN. Metabolic and scintigraphic studies of radioiodinated human C-reactive protein in health and disease. J Clin Invest 1993; 91(4): 1351-1357.
3. Pepys MB, Hirschfield GM. C-reactive protein: a critical update. J Clin Invest 2003; 111(12): 1805-1812.
4. Markanday A. Acute Phase Reactants in Infections: Evidence-Based Review and a Guide for Clinicians. Open Forum Infect Dis 2015; 2(3): ofv098.
5. Little P et al. Effects of internet-based training on antibiotic prescribing rates for acute respiratory-tract infections: a multinational, cluster, randomised, factorial, controlled trial. Lancet 2013; 382(9899): 1175-1182.
6. Tonkin-Crane SKG et al. Clinician-targeted interventions to influence antibiotic prescribing behaviour for acute respiratory infections in primary care: an overview of systematic reviews (Review). Cohcrane Database of Systematic Reviews 2017; 7(9): CD012252.
7. Bruns AH et al. Usefulness of consecutive C-reactive protein measurements in follow-up of severe community-acquired pneumonia. Eur Respir J 2008; 32(3): 726-732.
8. Verhagen DW et al. Prognostic value of serial C-reactive protein measurements in left-sided native valve endocarditis. Arch Intern Med 2008; 168(3): 302-307.
9. Emery P. Evidence-based review of biologic markers as indicators of disease progression and remission in rheumatoid arthritis. Rheumatol Int 2007; 27(9): 793-806.

Antimicrobial resistance is a global health threat. CRP point of care testing aids management of respiratory infections and fighting against antimicrobial resistance.
Learn more: Antimicrobial resistance and CRP

Marketing and sales materials

QuikRead go easy CRP Brief Instructions (EN)

QuikRead go easy CRP Control Procedure Brief Instructions (EN)

QuikRead go Family Brochure (EN)

QuikRead go Technical Specifications (EN)

QuikRead go Sample Collector Blood Sampling Instructions (EN)

QuikRead go Control Information (EN)

QuikRead go workstation Flyer (EN)

Videos

Instructions for use

(For informative use only. Kindly always refer to the latest package insert in the kit.)

QuikRead go easy CRP IFU (GB, DE, FR, IT), 153287

QuikRead go easy CRP IFU (FI, SE, NO, DK), 153287

QuikRead go easy CRP IFU (NL, ES, EE, LT), 153287

QuikRead go easy CRP IFU (CZ, SK, HU, PL), 153287

QuikRead go easy CRP IFU (HR, RS, RO, GB), 153287

QuikRead go CRP Controls IFU (GB, DE, FR, ES, IT, CZ, HU, PL, SK, NL, EE, LT, SE, NO, DK, FI), 153765, 153764, 153763

Safety Data Sheet

QuikRead go easy CRP SDS (EN) 153287

QuikRead go CRP Control High SDS (EN) 153763

QuikRead go CRP Control SDS (EN) 153764

QuikRead go CRP Control Low SDS (EN) 153765

I would like to start using the QuikRead go easy CRP test. Which instrument software version I need on my QuikRead go instrument?

You should have the version 7.6.2. or newer. This software is suitable also for all of the other test kits that we provide.

Can I store QuikRead go easy CRP kits at room temperature?

Yes, the unopened kits can be stored at cool or room temperature (2…25 ºC) until the expiry date marked on the kit label. After the first opening of the kit components, the cuvettes can be kept at room temperature (18…25 ºC) for 3 months. The reagent caps for 6 months. The sample collectors can be stored at 2…25 ºC until the expiry date of the kit. See more information in the package insert.

Why does the sample collector not disturb the measurement?

The sample collector stays in the cuvette during the whole measurement. The accuracy of the measurement is not affected because the sample collector does not hit the light path of the instrument.

Which sampling device is suitable for the QuikRead go easy CRP test?

QuikRead go Sample Collectors 10µl, which are included in the QuikRead go easy CRP test kit, must be used for sampling and adding the sample or control into the QuikRead go easy CRP cuvettes. Other sampling devices or capillaries are not suitable for this test.